Yuxiao Chen


I am a postdoctoral research fellow in the lab of Dr. Shreejoy Tripathy at the Krembil Centre for Neuroinformatics. My PhD was in a traditional wet-lab headed by Dr. Amy J. Ramsey in the University of Toronto, where I studied a genetic mouse model of cognitive impairment and its molecular, cellular, and behavioural changes. I am excited about using both experimental and computational methods to answer questions in neuroscience that take into account multiple scales of experiments and data.

Research Project

I currently study the relationship between gene expression and neuronal electric signaling in the brain, particularly by direct assessments via a technique known as Patch-seq. As part of my research, I am working on a clear and concise protocol for assessing and understanding the quality of Patch-seq data intrinsically and in contrast to public gene expression datasets. This will help connect traditional experimentalists to computational methods and increase the integration of different types of data for answering important questions in neuroscience.

Check out Yuxiao’s presentation of his CONP project in a short talk entitled “Improving the quality, documentation, and dissemination of multimodal single cell data”.