Expression-based Polygenic Risk Score Workshop

Date(s) - 03/11/2020
12:00 am - 2:30 pm


Don’t miss this great upcoming workshop on expression-based Polygenetic Risk Scores (ePRS). McGill’s Quantitative Life Sciences (QLS) PHD program, the Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM), the McGill initiative in Computational Medicine (MiCM), and the Ludmer Center for Neuroinformatics & Mental Health have join forces to offer weekly interdisciplinary seminars.  The tutorial was developed in collaboration with the  Canadian Open Neuroscience Platform (CONP). 

Who should attend: Researchers and trainees, globally,  who plan to or are considering applying Polygenetic Risk Scores (PRS) to their data and want to learn more about a novel, but proven biologically, expression-based Polygenetic Risk Scores (ePRS). This multimodal ePRS approach moves beyond the analysis of single genes, found in classical PRS methods, to enable researchers to associate a gene network with behavioural and brain imaging phenotypes.

3 November 2020 — 12:00 to 2:30pm

  • 12:00-100 pm,  Method Lecture: Deriving biologically-informed, expression-based Polygenic Risk Scores (ePRS)
  • 1:00-1:15 pm: Break to get your lunch and a coffee
  • 1:15-1:30 pm Lunch session: Introduction to the free  CONP resources, where you can download the ePRS-5HTT and other open-source tools and open-science datasets.
  • 1:30-2:30 pm,  ePRS-5-HTT Tutorial: What is a brain-region-specific expression-based polygenic score? Calculating the amygdala-based 5HTT ePRS in your data

Register via EventBrite: EventBrite Website

Guest Speaker: Patricia Pelufo Silveira MD, MSc, PhD is an Assistant Professor in the Department of Psychiatry at McGill University, leads the Environmental Adversity, Neurodevelopment and Mental Health theme-based group at the Douglas Mental Health University Institute, and is the Scientific Director (Int) of the Genomic & Epigenetics Pillar at the Ludmer Centre for Neuroinformatics & Mental Health.

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