Open neuroscience is a collective effort that requires extensive coordination between multiple organizations and across geographical boundaries to promote important discoveries and protect data value. The CONP Portal will provide infrastructure that will allow interoperability of neuroscience datasets across data modalities, timescales, and experimental models. In addition to dissemination and aggregation of research objects, the CONP Portal will enhance and extend the data management lifecycle by providing access to analytical tools and pipelines, and interactive environments for scholarly communication and collaboration.